Search results for " echo-planar imaging"

showing 2 items of 2 documents

Liver methylene fraction by dual- and triple-echo gradient-echo imaging at 3.0T: Correlation with proton MR spectroscopy and estimation of robustness…

2011

Purpose To assess the systematic errors in liver methylene fraction (LMF) resulting from fat–fat interference effects with dual- and triple-echo gradient-recalled-echo Dual/Triple GRE) sequences and to test the robustness of these sequences after iron overloading. Materials and Methods Forty type-2 diabetic patients underwent LMF measurement by 3.0T 1H magnetic resonance spectroscopy (corrected for T1 and T2 decays) as the reference standard and liver fat fraction (%Fat) measurement by four Dual/Triple GRE sequences with 20° and 60° flip angle (α), corrected for T1 recovery. The same four sequences were repeated in eight patients after ferumoxide injection. Corrections for systematic errors…

MaleMagnetic Resonance SpectroscopyMESH : Fatty LiverMESH: Echo-Planar Imaging[SDV]Life Sciences [q-bio]Carbon Compounds InorganicMESH : Statistics as TopicStatistics as TopicMESH : AgedContrast MediaMESH : Carbon Compounds InorganicMESH : Tissue Distribution030218 nuclear medicine & medical imagingCorrelationchemistry.chemical_compound0302 clinical medicineMESH : DextransNon-alcoholic Fatty Liver DiseaseMESH : FemaleTissue DistributionMESH: DextransMethyleneMagnetite NanoparticlesMESH: Fatty LiverMESH: AgedMESH: Middle Agedmedicine.diagnostic_testEcho-Planar ImagingDextransNuclear magnetic resonance spectroscopyMESH : AdultMiddle AgedMESH: Reproducibility of ResultsAdipose TissueLiverFemale030211 gastroenterology & hepatologyMESH : Sensitivity and SpecificityProtonsMESH: Adipose TissueAdultIron OverloadMESH : MaleMESH: Magnetite NanoparticlesMESH : Adipose TissueSensitivity and SpecificityMESH: Iron Overload03 medical and health sciencesFlip angleRobustness (computer science)MESH: Contrast MediaLinear regressionmedicineMESH : ProtonsHumansMESH : Middle AgedRadiology Nuclear Medicine and imagingMESH: Tissue DistributionMESH: Statistics as TopicAgedMESH : Contrast MediaMESH : Iron OverloadMESH: HumansMESH : Echo-Planar Imaging[ SDV ] Life Sciences [q-bio]MESH: Magnetic Resonance Spectroscopybusiness.industryMESH : Reproducibility of ResultsMESH : HumansMESH: Biological MarkersMESH: Carbon Compounds InorganicMESH : LiverMESH : Magnetite NanoparticlesReproducibility of ResultsMESH: AdultMagnetic resonance imagingMESH: MaleMESH: Sensitivity and SpecificityProton mr spectroscopyMESH : Biological MarkersFatty LiverchemistryMESH : Magnetic Resonance SpectroscopyMESH: ProtonsNuclear medicinebusinessMESH: FemaleBiomarkersMESH: LiverJournal of Magnetic Resonance Imaging
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Mathematical models for the diffusion magnetic resonance signal abnormality in patients with prion diseases

2014

In clinical practice signal hyperintensity in the cortex and/or in the striatum on magnetic resonance (MR) diffusion-weighted images (DWIs) is a marker of sporadic Creutzfeldt–Jakob Disease (sCJD). MR diagnostic accuracy is greater than 90%, but the biophysical mechanisms underpinning the signal abnormality are unknown. The aim of this prospective study is to combine an advanced DWI protocol with new mathematical models of the microstructural changes occurring in prion disease patients to investigate the cause of MR signal alterations. This underpins the later development of more sensitive and specific image-based biomarkers. DWI data with a wide a range of echo times and diffusion weightin…

MalePathologysCJD sporadic Creutzfeldt–Jakob diseaseROI region of interestPrion diseasePrPSc prion protein scrapieElectroencephalographyFOV field of viewlcsh:RC346-429Prion DiseasesADC apparent diffusion coefficientTI inversion timeRPE rapidly progressive encephalopathyAged 80 and overTE echo timeBrain Mappingmedicine.diagnostic_testBrainRegular ArticleMiddle AgedBIC Bayesian information criterionTR repetition timemedicine.anatomical_structureNeurologylcsh:R858-859.7FemaleMPRAGE magnetization-prepared rapid acquisition gradient-echoAbnormalitySS-SE single shot spin-echoAdultmedicine.medical_specialtyCognitive NeuroscienceCreutzfeldt–Jakob diseaseCNR contrast to noise ratioEPI echo-planar imagingNeuropathologyPrPC prion protein cellularGrey matterSpongiform degenerationlcsh:Computer applications to medicine. Medical informaticsEEG electroencephalogramDiffusion MRINeuroimagingImage Interpretation Computer-AssistedmedicineHumansRadiology Nuclear Medicine and imaginglcsh:Neurology. Diseases of the nervous systemAgedCJD Creutzfeldt–Jakob diseaseGSS Gerstmann–Sträussler–Scheinker syndromebusiness.industryDWI diffusion weighted imagingDiffusion MRI; Biophysical models; Creutzfeldt-Jakob disease; Prion disease; Spongiform degenerationMagnetic resonance imagingModels TheoreticalHyperintensityCreutzfeldt-Jakob diseaseDiffusion Magnetic Resonance ImagingNeurology (clinical)businessBiophysical modelsDiffusion MRINeuroImage: Clinical
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